Retrospective study of polytrauma patients's medical records that presented abdominal trauma, comperad to abdominal trauma and extra-abdominal injuries

This study sought to retrospectively assess the relationship between intra and extra-abdominal injuries in polytrauma patients undergoing laparotomy at the Regional University Hospital of Maringá between 2017 and 2018.This study was based on 111 electronic medical records from the Brazilian public health system "SUS", admitted to the hospital due to trauma and undergoing laparotomy, comparing two groups: abdominal injury without extra-abdominal injury (WoEI) and abdominal injury with extra-abdominal injury (WiEI).A total of 111 medical records were analyzed, 57 from 2017 and 54 from 2018. Of these 111records, 43 (39%) were trauma victims with only abdominal injuries and 68 (61%) trauma victims with abdominal and extra-abdominalinjuries. Most patients were male (85%), with an average age of 33 years, ranging from 14 to 87 years. In statistical analysis, according to the T-test, there was significance (p > 0.05) between the WoEI and WiEI groups for data collected regarding death rates and hospitalization days. As for the morbidity rate and difference between genders (male and female), there was no statistical significance (p < 0.05).Polytraumapatients are exposed to greater kinetic energy, with more severe conditions and therefore required more in-hospital care.

Trauma de vena cava en pacientes politraumatizados: experiencia en el Hospital Dr. Sótero del Río / Vena cava injury in politraumatized patients

Resumen Introducción Por su ubicación retroperitoneal, las lesiones de vena cava (LVC) son infrecuentes, presentándose en el contexto de un paciente con múltiples lesiones intraabdominales y en estado crítico. Objetivo Describir la experiencia de pacientes politraumatizados con LVC sometidos a resolución quirúrgica en Hospital Dr. Sotero del Río. Materiales y Método Análisis retrospectivo de 36 pacientes politraumatizados que dentro de la intervención quirúrgica se evidenció LVC en un período comprendido entre el 2010 y 2017. Resultados La serie estuvo compuesta por 36 pacientes, con LVC. El 88,8% son hombres, en el 97,2% el mecanismo de trauma es penetrante. Dentro de los niveles anatómicos vasculares más frecuentemente lesionados está la cava infrarrenal (41,6%), suprarrenal (25%), yuxtarrenal (22,2%) y la retrohepática e intratorácica (5,5% cada una). Las estructuras lesionadas asociadas más frecuentes fueron intestino delgado (38,8%), otros vasos de gran calibre (36,1%) y riñón (30,5%). Dentro del tipo de resolución quirúrgica, al 15,6% se realizó ligadura de vena cava y al 83,3% rafia simple. En 33,3% fue necesaria una toracotomía para el control vascular, siendo 2 de estas toracotomías resucitadoras. La media de hospitalización fue de 19,8 días. La mortalidad fue de 33,3%. Conclusiones De acuerdo a lo presentado, la alta mortalidad de LVC se encontró en el grupo de pacientes con inestabilidad hemodinámica y número de lesiones asociadas, en especial si involucran otros grandes vasos. Los esfuerzos para optimizar la supervivencia se deberían dirigir al traslado rápido prehospitalario y al entrenamiento de los cirujanos que enfrentan este tipo de lesiones.

Introduction For its retroperitoneal location, vena cava injuries are infrequent, however, occurring to a patient with multiple intra-abdominal injuries and in critical condition. Aim To describe the experience of polytraumatized patients with VCI who underwent surgical resolution in the Dr. Sotero del Rio hospital. Materials and Method Retrospective analysis of 36 polytraumatized patients that showed VCI during the surgical intervention within 2010 and 2017. Results The series was composed of 36 VCI patients. 88.8% are men, in 97.2% the mechanism of trauma is penetrating. Within the vascular anatomical levels, the most frequently injured are the infra-renal cava (41.6%) suprarenal (25%), yuxta-renal (22.2%) retro-hepatic and intrathoracic (5.5% each). The most frequent associated injured structures were the small intestine (38.8%) other vessels of large caliber (36.1%) and kidney (30.5%). In relation to the type of surgical resolution, 15.6% had a vena cava ligature and 83.3% simple raffia. In 33.3%, a thoracotomy was required for vascular control, two of them were resuscitative procedures. The average of hospitalization was 19.8 days. The mortality was 33.3%. Conclusions According to what presented, the high mortality of VCI was found in the group of patients with hemodynamic instability and the number of associated injuries; specially if other large vessels are involved. To optimize the survival, the efforts should be focused on a fast prehospital transfer and the training for surgeons who face this type of injury.

Serum levels of NLRP3 and HMGB-1 are associated with the prognosis of patients with severe blunt abdominal trauma

OBJECTIVES: To investigate the relationship between the serum levels of NLRP3 and HMGB-1 and the prognosis of patients with severe blunt abdominal trauma. METHODS: In total, 299 patients were included in the current study from July 2014 to December 2015. All patients were divided into the mild/moderate blunt abdominal trauma group and the severe blunt abdominal trauma group according to their injury severity scores. Serum levels of NLRP3 and HMGB-1 were measured upon admission (0 h) and at 12 h, 24 h, 48 h, 72 h and 7 days after admission. RESULTS: Compared with the healthy controls, both the mild/moderate and severe blunt abdominal trauma groups had higher serum levels of NLRP3 and HMGB-1 at admission. At all points, the serum levels of NLRP3 and HMGB-1 were significantly higher in the severe group than in the mild/moderate group. The serum levels of both NLRP3 and HMGB-1 were significantly higher in the deceased patients than in the living patients. The Kaplan-Meier curve showed that compared with patients with higher levels of NLRP3 or HMGB-1, those with lower levels had longer survival times. The serum levels of both NLRP3 and HMGB-1 were independent risk factors for 6-month mortality in severe blunt abdominal trauma patients. CONCLUSION: The serum levels of NLRP3 and HMGB-1 were significantly elevated in severe blunt abdominal trauma patients, and the serum levels of both NLRP3 and HMGB-1 were correlated with 6-month mortality in severe blunt abdominal trauma patients.

Influência do local de origem do trauma nos índices de admissão de pacientes submetidos à laparotomia de emergência / Influence of trauma origin site on admission rates of patients submitted to emergency laparotomy

RESUMO Objetivo: avaliar a influência do local de ocorrência do trauma nos escores de trauma de pacientes submetidos à laparotomia de emergência. Métodos: estudo retrospectivo observacional analítico. Foram incluídos 212 pacientes submetidos à laparotomias exploratórias no período de janeiro de 2015 e dezembro de 2017. Informações sobre o local do acidente e dados vitais dos pacientes foram obtidas com base na coleta de dados por meio de prontuários eletrônicos e físicos. Foram analisados os índices de trauma de pacientes provenientes de Curitiba e Região Metropolitana e o local em que o paciente foi socorrido (estabelecimento físico ou via pública). Resultados: entre os 212 pacientes estudados, 184 (86,7%) foram trazidos pelo Serviço de Atendimento Pré-Hospitalar provenientes da cidade Curitiba e 28 (13,3%) provenientes de Região Metropolitana de Curitiba. Foram socorridos em estabelecimentos físicos 25 pacientes (17,6%), enquanto 117 (82,4%) foram socorridos em via pública. Observou-se maiores valores de ISS (Injurity Severity Score) dos pacientes procedentes da Região Metropolitana em relação aos procedentes de Curitiba (29,78 vs 22,46, P=0,009), enquanto valores maiores do TRISS (Trauma Trauma and Injury Severity Score) foram observados em pacientes procedentes de Curitiba em relação aos da Região Metropolitana (90,62 vs 81,30; P=0,015). Pacientes socorridos em via pública apresentaram menor valor de RTS (Revised Trauma Score) (6,96 vs 7,65; P=0,024) e TRISS (86,42 vs 97,21; P=0,012). Conclusão: pacientes vítimas de trauma procedentes de locais mais distantes do atendimento no centro de referência apresentaram pior prognóstico à admissão e foi observado pior prognóstico em pacientes socorridos em via pública.

ABSTRACT Objective: to evaluate the influence of the site of trauma occurrence on the trauma scores of patients submitted to emergency laparotomy. Methods: this is a retrospective, observational, analytical study. We included 212 patients who underwent exploratory laparotomies in the period of January 2015 and December 2017. We obtained information about the accident site and vital data of the patients based on data collection through electronic and physical records. We analyzed the trauma indices of patients from Curitiba and its Metropolitan Region and the place where the patient was rescued (physical establishment or public road). Results: among the 212 patients studied, 184 (86.7%) were brought by the Prehospital Care Service from the city of Curitiba, and 28 (13.3%), from the Metropolitan Region of Curitiba. Twenty-five patients (17.6%) were rescued in physical establishments, while 117 (82.4%) were rescued on public roads. We observed higher values ​​of Injurity Severity Scores (ISS) in patients coming from the Metropolitan Region than in those coming from Curitiba (29.78 vs 22.46, P=0.009), but higher values ​​of Trauma and Injury Severity Scores (TRISS) in patients from Curitiba than the ones from the Metropolitan Region (90.62 vs 81.30, P=0.015). Patients rescued in public roads presented lower Revised Trauma Scores (RTS) (6.96 vs 7.65, P=0.024) and TRISS (86.42 vs 97.21; P=0.012). Conclusion: trauma victims from sites more distant from the referral center and rescued on public roads presented worse prognosis.

Deaths from abdominal trauma: analysis of 1888 forensic autopsies / Óbitos por trauma abdominal: análise de 1888 autopsias médico-legais

ABSTRACT Objective: to evaluate the epidemiological profile of deaths due to abdominal trauma at the Forensic Medicine Institute of Belo Horizonte, MG - Brazil. Methods: we conducted a retrospective study of the reports of deaths due to abdominal trauma autopsied from 2006 to 2011. Results: we analyzed 1.888 necropsy reports related to abdominal trauma. Penetrating trauma was more common than blunt one and gunshot wounds were more prevalent than stab wounds. Most of the individuals were male, brown-skinned, single and occupationally active. The median age was 34 years. The abdominal organs most injured in the penetrating trauma were the liver and the intestines, and in blunt trauma, the liver and the spleen. Homicide was the most prevalent circumstance of death, followed by traffic accidents, and almost half of the cases were referred to the Forensic Medicine Institute by a health unit. The blood alcohol test was positive in a third of the necropsies where it was performed. Cocaine and marijuana were the most commonly found substances in toxicology studies. Conclusion: in this sample. there was a predominance of penetrating abdominal trauma in young, brown and single men, the liver being the most injured organ.

RESUMO Objetivo: avaliar o perfil epidemiológico dos óbitos por trauma abdominal no Instituto Médico Legal de Belo Horizonte. Métodos: estudo retrospectivo dos laudos de óbitos relacionados a trauma abdominal necropsiados no período de 2006 a 2011. Resultados: foram analisados 1888 laudos necroscópicos de trauma abdominal. O trauma penetrante foi mais comum que o contuso, e o decorrente de projéteis de arma de fogo mais prevalente que o relacionado a armas brancas. A maioria dos indivíduos era do sexo masculino, morena, solteira e ativa do ponto de vista ocupacional. A média etária foi de 34 anos. O homicídio foi a circunstância do óbito mais prevalente, seguido dos acidentes de trânsito, e quase a metade dos casos foi recebida no Instituto Médico Legal proveniente de uma unidade saúde. Os órgãos abdominais mais lesados no trauma penetrante foram o fígado e os intestinos, e no trauma contuso foram o fígado e o baço. A pesquisa de alcoolemia foi positiva em um terço das necropsias onde foi realizada. Cocaína e maconha foram as substâncias mais encontradas nos exames toxicológicos. Conclusão: nesta amostra houve predominância do trauma abdominal penetrante, em homens jovens, morenos e solteiros, sendo o fígado o órgão mais lesado.

Risk factors for mortality in blunt abdominal trauma with surgical approach / Fatores de risco para óbito no trauma abdominal fechado com abordagem cirúrgica

ABSTRACTObjective:identify risk factors for mortality in patients who underwent laparotomy after blunt abdominal trauma.Methods:retrospective study, case-control, which were reviewed medical records of blunt trauma victims patients undergoing laparotomy, from March 2013 to January 2015, and compared the result of the deaths group with the group healed.Results:of 86 patients, 63% were healed, 36% died, and one patient was excluded from the study. Both groups had similar epidemiology and trauma mechanism, predominantly young adults males, automobilistic accident. Most cases that evolved to death had hemodynamic instability as laparotomy indication - 61% against 38% in the other group (p=0.02). The presence of solid organ injury was larger in the group of deaths - 80% versus 48% (p=0.001) and 61% of them had other associated abdominal injury compared to 25% in the other group (p=0.01). Of the patients who died 96% had other serious injuries associated (p=0.0003). Patients requiring damage control surgery had a higher mortality rate (p=0.0099). Only one of 18 patients with isolated hollow organ lesion evolved to death (p=0.0001). The mean injury score of TRISS of cured (91.70%) was significantly higher than that of deaths (46.3%) (p=0.002).Conclusion:the risk factors for mortality were hemodynamic instability as an indication for laparotomy, presence of solid organ injury, multiple intra-abdominal injuries, need for damage control surgery, serious injury association and low index of trauma score.

RESUMOObjetivo:identificar fatores de risco para óbito em pacientes submetidos à laparotomia exploradora após trauma abdominal contuso.Métodos:estudo retrospectivo, caso-controle, no qual foram revisados prontuários dos pacientes vítimas de trauma contuso submetidos à laparotomia. Foram avaliados: variáveis epidemiológicas, mecanismo de trauma, lesões anatômicas das vísceras abdominais, lesões associadas, necessidade de operação para controle de danos reoperação e desfecho.Resultados:dos 86 pacientes, 63% foram curados, 36% foram a óbito e um paciente foi excluído do estudo. Ambos os grupos possuíam epidemiologia e mecanismo de trauma semelhantes, predominantemente adultos jovens do sexo masculino, vítimas de acidente automobilístico. A maioria dos casos que evoluíram a óbito teve instabilidade hemodinâmica como indicação de laparotomia - 61% contra 38% do outro grupo. A presença de lesão de víscera maciça foi maior no grupo óbitos - 80% vs. 48%, e 61% destes tinham outra lesão abdominal associada contra 25% dos curados. Dos pacientes que faleceram, 96% apresentavam lesões graves associadas. Pacientes que necessitaram de cirurgia de controle de danos tiveram maior taxa de mortalidade. Apenas um de 18 pacientes com lesão de víscera oca isolada evoluiu a óbito. A média do escore de trauma TRISS dos curados (91,7%) foi significativamente maior do que a dos óbitos (46,3%).Conclusão:os fatores de risco para óbito encontrados para vítimas de trauma abdominal fechado que necessitam de laparotomia exploradora são: instabilidade hemodinâmica como indicação para laparotomia, presença de lesão de víscera maciça, múltiplas lesões intra-abdominais, necessidade de cirurgia de controle de danos, lesões graves associadas e índice de trauma baixo.

Estudo da morbimortalidade em pacientes com trauma hepático / Morbimortality in patients with hepatic trauma

RACIONAL: O fígado é o órgão intra-abdominal mais comumente lesado em pacientes vítimas de trauma. A lesão ocorre mais frequentemente no trauma penetrante do que no contuso. A mortalidade é de 10%. OBJETIVO: Avaliar a morbimortalidade dos pacientes com trauma hepático, o manuseio aplicado a esses pacientes e sua evolução. MÉTODO: Foram analisados, retrospectivamente, os prontuários de todos os pacientes com trauma hepático e indicação cirúrgica, admitidos na emergência. Consideraram-se: sexo, faixa etária, ISS (injury severity score), classificação do tipo de trauma abdominal (aberto ou fechado), instrumento causador dos traumas abertos, grau da lesão, segmentos hepáticos envolvidos, presença de lesões associadas, tipo de tratamento cirúrgico realizado: laparotomia não-terapêutica e laparotomia terapêutica, reoperações, complicações, tempo de internamento em dias e mortalidade. RESULTADOS: Cento e trinta e sete pacientes participaram do estudo. Destes, 124 eram do sexo masculino (90,5%). Quanto à faixa etária, a maioria (56,2%) encontrava-se entre 20-29 anos. O trauma abdominal fechado foi o mais comum (67,9%). Dos penetrantes, os originados por arma de fogo foram em maior número (24,8%). Cento e três pacientes apresentaram apenas um segmento lesado (75,2%) e 34 (24,8%) dois. As lesões de grau II foram as mais comuns (66,4%). Dos 137 pacientes submetidos à laparotomia, 89 foram não-terapêutica, enquanto que em 48 foi necessário reparos das lesões associadas. O baço e o diafragma foram as estruturas lesadas com maior frequência, 30% e 26%, respectivamente. O ISS variou de oito a 72, sendo o ISS > 50 (oito pacientes) associado com evolução fatal (cinco pacientes). Fístula biliar e abscesso hepático foram as principais complicações. Ocorreram sete óbitos no estudo. CONCLUSÃO: Os pacientes com trauma hepático e lesões orgânicas concomitantes e naqueles com ISS > 50 observou-se maior chance de complicações e óbito.

BACKGROUND: The liver is the intra-abdominal organ more injured in patient victims of trauma. The injury occurs more frequently in the penetrating trauma. The incidence of mortality for injuries of the liver is 10%. AIM: To evaluate the mortality of the patients with hepatic trauma, the treatment applied and its evolution. METHODS: Were analyzed, retrospectively, the charts of all patients with hepatic trauma and surgical indication. Were analyzed: gender, age, ISS (injury severity score), classification of the abdominal trauma type (open or closed), causing instrument of the open traumas, degree of the injury, hepatic segments involved, presence of associated injuries, type of surgical treatment: not-therapeutic laparotomy and therapeutic laparotomy, reoperations, complications, time of hospitalization in days and mortality. RESULTS: One hundred and thirty-seven patients participated. Of these, 124 were men (90.5%). The majority (56.2%) had 20-29 years old. Closed abdominal trauma was most prevalent (67.9%). Of the penetrating traumas, the originated with firearms were in 24.8%. One hundred and three patients had only one injured hepatic segment (75.2%) and 34 (24.8%) two. Grade II injuries were in 66.4%. Of the 137 patients with laparotomy, 89 had been not-therapeutic, while in 48 it was necessary to repair associated injuries. Spleen and diaphragm had been the more frequently injured structures, 30% and 26%, respectively. The ISS varied of eight to 72, being the ISS > 50 (eight patients) associate with fatal evolution (five patients). Biliary fistula and hepatic abscess had been the main complications. Seven deaths had occurred. CONCLUSIONS: Concomitant injuries, hepatic and other organs, associated with ISS > 50 presented higher possibility of complications and death.

Victim profile and pattern of thoraco-abdominal injuries sustained in fatal road traffic accidents.

The present research aims to highlight the pattern of thoraco-abdominal injuries sustained by the victims of fatal road traffic accidents (RTA) in Manipal, South India. The study is an autopsy based observation of thoraco-abdominal injuries in victims of fatal road traffic accidents during 1999 – 2003. Road traffic accidents accounted for most of the injury related deaths (77%) during the study period. A male preponderance (86%) was observed with a male-female ratio of 6:1. Individuals in the age group of 21 to 50 years formed the most vulnerable (83%) group. External thoracic injuries were more common than internal thoracic injuries in the thoracic region. In the abdominal region, internal injuries were more common than external injuries. Lungs (61%) and kidneys (23%) were the most commonly involved organs in the thoracic and abdominal regions respectively. Majority of the victims were two wheeler occupants (35%) followed by pedestrians (23%). The study indicates the pattern of thoraco-abdominal injuries sustained along with the trend of road traffic accidents in the region.

Morbilidad y mortalidad por traumatismo con lesión visceral / Morbidity and Mortality due to Trauma with visceral injury

Se efectuó un estudio descriptivo y transversal de los pacientes con traumatismos abdominales ingresados en el Hospital Provincial Docente Dr Joaquín Castillo Duany de Santiago de Cuba, desde enero del 2002 hasta diciembre del 2009, para evaluar la morbilidad y mortalidad por traumas abdominales con lesión visceral. En la serie predominaron el sexo masculino, el grupo etario de 20-29 años, los traumas abdominales abiertos y la agresión con arma blanca. El intestino delgado y el hígado fueron las vísceras más lesionadas, en tanto que para el diagnóstico resultaron ser más útiles los elementos clínicos: dolor abdominal, reacción peritoneal y taquicardia. Entre las principales complicaciones prevalecieron la infección de la herida quirúrgica y el choque hipovolémico

A descriptive and cross-sectional study including patients with abdominal traumas admitted at Dr Joaquín Castillo Duany Teaching Provincial Hospital in Santiago de Cuba from January, 2002 to December, 2009 was carried out to assess the morbidity and mortality due to abdominal traumas with visceral injuries. In the series, male sex, age group from 20-29 years, open abdominal traumas and attacks using stabs were predominant. Small intestine and liver were the most affected viscera; while clinical aspects, such as abdominal pain, peritoneal reaction and tachycardia were more useful for the diagnosis. Among the main complications, the infection of surgical wound and the hypovolemic shock were predominant

Death due to isolated mesenteric vascular injury following blunt abdominal trauma: A case report.

Death due to isolated injury to small bowel mesentery following abdominal trauma is rare. It is known that seatbelt trauma from motor vehicle accidents is the most common mechanism of mesenteric injury and that the mesentery of the small bowel is injured more frequently than that of the colon. Focal mesenteric infiltration associated with haemoperitoneum, particularly in the absence of solid organ injury, is highly suggestive of a mesenteric tear. In this report one such seat belt abdominal injury with subsequent mesenteric tear and bowel infarction with significant haemoperitoneum leading to death on the Operation table is being discussed. The main significance of this injury is delay and difficulty in diagnosis, especially when there is minimal signs and symptoms to warrant an exploratory laparotomy. Early detection and emergency surgical intervention when necessary are critical in improving the outcome of treatment.

Blunt abdominal trauma requiring laparotomy in poly-traumatized patients

To investigate the impact of associated extra-abdominal injury on morbidity and mortality in poly-traumatized patients with blunt abdominal trauma. This analysis included poly-traumatized patients with blunt abdominal trauma treated at the Emergency Unit of Minia University Hospital and Misr University for Science and Technology Hospital, Minia, Egypt, between March 2006 and March 2008. This study included patients aged 4-73 years with injury severity score [ISS] more than 18 and indicated for surgical intervention. Data were analyzed with details of injury, treatment, complications, and mortality. Inclusion criteria were met by 94 patients with mean ISS of 29.3 +/- 6.4. Most frequent injuries were seen in the spleen [61.7%] and liver [47.9%]. Chest trauma represents most common extra-abdominal trauma [67%] Thirty-six patients [38.3%] died during their hospital stay. Most frequent reasons for death were hemorrhagic shock [27.8%], acute respiratory distress syndrome [27.8%], and head trauma [22.2%]. There was a positive relationship between liver injury and mortality, which not found in splenic injuries. Significantly more deaths were attributed to primarily extra-abdominal injuries [66.7%] and then to intra-abdominal injuries [19.4%]. In 5 patients [13.9%], a combination of intra- and extra- abdominal injuries caused post-traumatic death. Extra-abdominal injuries add to the morbidity and mortality from blunt abdominal trauma in poly-traumatized patients. Routine computerized tomography scanning can minimize negative abdominal exploration and facilitate better management of extra- abdominal injuries

The use of pyloric exclusion for treating duodenal trauma: case series / Exclusão pilórica no tratamento do trauma duodenal: série de casos

CONTEXT AND OBJECTIVES: Significant controversy exists regarding the best surgical treatment for complex duodenal injuries. The aims of this study were to report on a series of eight cases of duodenal repairs using pyloric exclusion and to describe reported complications or improvements in clinical outcomes among patients with complex duodenal trauma. DESIGN AND SETTING: Cross-sectional study followed by a case series in a university hospital. METHODS: Data on eight patients with duodenal trauma who underwent pyloric exclusion over a 17.5 year period were collected and analyzed. RESULTS: The causes of the injuries included penetrating gunshot wounds (GSW) in five patients and motor vehicle accidents (blunt trauma) in three patients. The time elapsed until surgery was longer in the blunt trauma group, while in one patient, the gunshot injury was initially missed and thus the procedure was carried out 36 hours after the original injury. The injuries were grade III (50 percent) or IV (50 percent) and the morbidity rate was 87.5 percent. Four patients (50 percent) died during the postoperative period from complications, including hypovolemic shock (one patient), sepsis (peritonitis following the missed injury) and pancreatitis with an anastomotic fistula (two patients). CONCLUSIONS: Pyloric exclusion was associated with multiple complications and a high mortality rate. This surgical technique is indicated for rare cases of complex injury to the duodenum and the surgeon should be aware that treatment with a minimalistic approach, with only primary repair, may be ideal.

CONTEXTO E OBJETIVOS: Há controvérsias a respeito do melhor tratamento cirúrgico para as lesões duodenais complexas. O objetivo deste estudo é relatar uma série de oito casos de reparo duodenal utilizando a exclusão pilórica e descrever a evolução dos pacientes com trauma duodenal complexo submetidos a este procedimento. TIPO DE ESTUDO E LOCAL: Estudo transversal e descrição de série de casos em hospital universitário. MÉTODOS: Foram coletadas e analisadas as informações de oito pacientes com trauma duodenal submetidos à exclusão pilórica em um período de 17,5 anos. RESULTADOS: Os mecanismos de trauma envolvidos foram ferimentos por projétil de arma de fogo em cinco pacientes e acidente automobilístico em três pacientes. O atraso do tratamento cirúrgico foi maior nos pacientes vítimas de trauma fechado, e em um paciente a lesão pelo projétil passou despercebida, sendo o procedimento cirúrgico realizado em nova laparotomia após 36 horas. As lesões duodenais encontradas foram grau III (50 por cento) ou grau IV (50 por cento), e a taxa de morbidade foi de 87,5 por cento. Quatro pacientes (50 por cento) morreram durante o período pós-operatório, de complicações como choque hipovolêmico (um caso), sepse (peritonite por ferimento não identificado), ou pancreatite associada à fístula da anastomose (dois casos). CONCLUSÕES: A exclusão pilórica esteve associada à alta taxa de morbimortalidade. Esta técnica cirúrgica deve ser indicada em poucos casos de lesão complexa de duodeno e o cirurgião deve saber que, frente a uma lesão duodenal, a sutura primária pode ser o melhor tratamento.

Sobrevivência após acidentes de trânsito: impacto das variáveis clínicas e pré-hospitalares / Survival after motor vehicle crash: impact of clinical and prehospital variables / Sobrevida después de accidentes de tránsito: impacto de las variables clínicas y pre hospitalarias

OBJETIVO: Analisar as variáveis clínicas e pré-hospitalares associadas à sobrevivência de vítimas de acidente de trânsito. MÉTODOS: Estudo realizado no município de São Paulo, SP, de 1999 a 2003. Foram analisados dados de 175 pacientes, entre 12 e 65 anos, vitimados por acidente de trânsito. A Análise de Sobrevivência de Kaplan-Meier foi utilizada na abordagem dos resultados na cena do acidente com as vítimas de escore <11 segundo o Revised Trauma Score. As variáveis analisadas foram: sexo, idade, mecanismos do acidente, procedimentos de suporte básico e avançado realizados, parâmetros e flutuações do Revised Trauma Score, tempo consumido na fase pré-hospitalar e gravidade do trauma segundo o Injury Severity Score e a Maximum Abbreviated Injury Scale. RESULTADOS: A análise identificou que as vítimas que tiveram menor probabilidade de sobrevivência durante todo período de internação hospitalar apresentaram: lesões graves no abdome, tórax ou membros inferiores, com flutuação negativa da freqüência respiratória e do Revised Trauma Score na fase pré-hospitalar e necessitaram de intervenções avançadas ou compressões torácicas. As lesões encefálicas foram associadas ao óbito tardio. CONCLUSÕES: O reconhecimento das variáveis envolvidas na sobrevivência de vítimas de acidentes de trânsito pode auxiliar na determinação de protocolos e na tomada de decisão para a realização de intervenções pré e intra-hospitalares e conseqüentemente maximizar a sobrevivência.

OBJECTIVE: To assess clinical and prehospital variables associated with survival of motor vehicle crash victims. METHODS: Study carried out in the city of São Paulo (Southeastern Brazil), from 1999 to 2003. Data from 175 patients, who were aged between 12 and 65 years and had been motor vehicle crash victims, were analyzed. Kaplan-Meier Survival Analysis was used to approach the results at the accident scene with victims scoring <11, according to the Revised Trauma Score. Variables analyzed were: sex, age, injury mechanisms, basic and advanced support procedures, Revised Trauma Score parameters and fluctuations, time elapsed in the prehospital phase and trauma severity according to the Injury Severity Score and Maximum Abbreviated Injury Scale. RESULTS: Analysis revealed that victims who were less likely to survive during the hospitalization period showed serious lesions in the abdomen, thorax, or lower limbs, with negative fluctuation of respiratory frequency and Revised Trauma Score in the prehospital phase. In addition, they needed specialized interventions or thoracic compressions. Brain lesions were associated with late death. CONCLUSIONS: Recognition of variables involved in the survival of motor vehicle crash victims may help to determine protocols and to make decisions in order to perform pre- and in-hospital interventions and, consequently, maximize survival.

OBJETIVO: Analizar las variables clínicas y pre hospitalarias asociadas a la sobrevida de víctimas de accidentes del tránsito. MÉTODOS: Estudio realizado en el municipio de São Paulo (Sudeste de Brasil), de 1999 a 2003. Fueron analizados datos de 175 pacientes, entre 12 y 65 años, victimas de accidentes de tránsito. El análisis de Sobrevida de Kaplan-Meier fue utilizado en el abordaje de los resultados en la escena del accidente con las víctimas de score <11 segun el Revised Trauma Score. Las variables analizadas fueron: sexo, edad, mecanismos del accidente, procedimientos de soporte básico y avanzado realizados, parámetros y fluctuaciones del Revised Trauma Score, tiempo consumido en la fase pre hospitalaria y gravedad del trauma según el Injury Severity Score y la Maximum Abbreviated Injury Scale. RESULTADOS: El análisis identificó que la víctimas que tuvieron menor probabilidad de sobre vivencia durante todo el período de interacción hospitalaria presentaron: lesiones graves en el abdomen, tórax o miembros inferiores, con fluctuación negativa de la frecuencia respiratoria y del Revised Trauma Score en la fase pre hospitalaria y necesitaron de intervenciones avanzadas o compresiones torácicas. Las lesiones encefálicas fueron asociadas al óbito tardío. CONCLUSIONES: El reconocimiento de las variables involucradas en la sobrevida de víctimas de accidentes del tránsito puede auxiliar en la determinación de protocolos y en la toma de decisiones para la realización de intervenciones pre e intra-hospitalarias y consecuentemente maximizar la sobrevida.

Blunt abdominal trauma with small bowel injury: are isolated lesions riskier than associated lesions?

PURPOSE: The objective of this study was to compare patients with "isolated" blunt small bowel injury (SBI) to patients with multiple intra-abdominal injuries and analyze whether delayed laparotomy affected outcome. METHODS: Medical records of patients that suffered a blunt SBI between 1994 and 2005 were reviewed. The patients were divided into two groups: those with isolated SBI and those with other associated intra-abdominal injuries ("non-isolated"). The method of diagnosis, time to operation, small bowel Organ Injury Scale (OIS) assessment (grade > 2), injury severity score (ISS), morbidity, and mortality were analyzed. RESULTS: A total of 90 patients met the inclusion criteria, including 62 (68.9 percent) isolated cases and 28 (31.1 percent) non-isolated cases. Isolated cases required more supplementary diagnostic methods than the non-isolated cases. Non-isolated cases had a shorter diagnosis to treatment period (p < .01) and a higher ISS (mean 22.5 vs. 17.2 in "isolated" group). Morbidity (51.6 percent and 53.6 percent) and mortality (16.1 percent and 28.6 percent) did not differ significantly between the isolated and non-isolated groups. Delays in diagnosis were common in the isolated group, but this did not affect outcome. Patients with associated injuries, and higher ISS, had higher mortality. CONCLUSIONS: The presence of associated intra-abdominal injuries significantly affected the presentation and time to diagnosis of patients with SBI, but not morbidity or mortality. Delayed surgical treatment in the isolated cases was not associated with an increased incidence of complications. Patients inflicted with more severe associated injuries were less likely to survive the trauma.

OBJETIVO: Comparar pacientes com lesão "isolada" de intestino delgado com pacientes com lesões abdominais "associadas" e analisar o quanto o retardo para indicação de laparotomia influenciou na evolução dos pacientes. MÉTODOS: Foram revisados os prontuários de pacientes com trauma abdominal fechado e lesão de intestino delgado no período de 1994 a 2005, sendo os pacientes divididos em dois grupos: lesão "isolada" e lesões abdominais "associadas". Foram analisados os métodos diagnósticos, intervalo de tempo para a cirurgia, gravidade da lesão de delgado (grau > 2), ISS e morbimortalidade dos pacientes. RESULTADOS: Noventa pacientes preencheram os critérios de inclusão, 62 (68,9 por cento) no grupo "isolada" e 28 (31,1 por cento) no "associada". Pacientes do grupo "isolada" necessitaram mais de métodos diagnósticos complementares. O tempo de diagnóstico até o tratamento foi significantemente menor no grupo "associada", e estes pacientes apresentavam ISS mais elevado (média de 22,5 versus 17,2 no grupo "isolada"). A morbidade e mortalidade nos grupos foram, respectivamente, 51,6 por cento e 16,1 por cento no grupo "isolada", e 53,6 por cento e 28,6 por cento no "associada", sem diferença estatística. Demora para o diagnóstico foi comum no grupo "isolada", porém sem agravar a evolução dos pacientes. Pacientes com lesões "associadas", quantificadas pelo ISS, tiveram maior mortalidade. CONCLUSÃO: A presença de lesões abdominais "associadas" significativamente interferiu no quadro clínico e momento do diagnóstico em pacientes com lesão de delgado, porém não influenciou na morbimortalidade. No grupo "isolada" a demora para tratamento cirúrgico foi freqüente, porém sem interferir nas complicações. A elevada mortalidade foi reflexo da gravidade de lesões associadas.

Penetrating colonic injuries in wartime; our experiences in Al Yarmouk Teaching Hospital, Baghdad

Penetrating trauma is the commonest cause of surgical admissions in Baghdad following invasion to Iraq 2003. In this study, the factors that affect the morbidity and mortality in patients with penetrating colonic injuries were evaluated. Eighty six [86] patients [74 males, 12 females; age range 7 to 60 years] with penetrating colonic trauma, most of them of high velocity injuries were evaluated according to age, gender, type of penetration, trauma location and severity of colonic injury, associated injury, interval between the trauma and definitive operation, hemodynamic status, blood transfusion requirement, fecal contamination, surgical procedure, postoperative complication and mortality. The mechanisms of injuries were bullets injury in 66 [76.74%] patients, blast injury [shell] in 18 [ 20.93%] and stab injury in 2 [2.3%] patients. Injuries were evaluated according to TRISS and PATI [penetrating abdominal trauma index]. Multiple organs injuries found in 68 [79%] patients, wherease only the large bowels injured in 18 [21%] patients. Primary repair was performed in 36 [42%] of the 86 patients, and colostomy was performed in 50[58%] patients. From those with primary closure [36 patients], PATI was over 25 in 10 patients and below 25 in 26 patients. 15 patients had resection segment [destructive injuries, primary anastomosis], 7 patients had more than 25% of colonic wall injuries, and 10 had less than 25%. Symptoms of shock were present in 66 patients at admission, mortality rate was 6.97%. These results suggest that the use of primary closure should be expanded in penetrating colon trauma and that, even with moderate and severe degrees of colon injury, primary closure provides an outcome equivalent to that provided by colostomy. The primary repair of the penetrating colon trauma can be performed confidently in patients with PATI suggests that is should be included along with other injury severity indices in trauma data bases

Effect of oral glutamine administration on oxidative stress, morbidity and mortality in critically ill surgical patients.

OBJECTIVE: To examine the effect of enteral administration of glutamine in patients with peritonitis or abdominal trauma. METHODS: In a prospective, interventional, observer-blind, randomized clinical trial, 120 patients, aged 18-60 years, were randomized to receive either enteral glutamine 45 g/day for 5 days in addition to standard care (n=63; group A) or standard care alone (n=57; group B). Surgical intervention was done as needed. RESULTS: The two groups were comparable for sex and severity of illness scores. Following treatment, serum malondialdehyde (MDA) levels in group A increased from 4.4 (8.0) to 7.2 (4.8) mmol/mL, whereas those in group B decreased from 3.9 (4.9) to 3.1 (5.0) mmol/mL; these changes were not statistically significant. Reduced glutathione levels increased from 0.03 (0.04) to 0.06 (0.12) mg/g Hb (p=0.032) after treatment in group A and from 0.03 (0.03) to 0.05 (0.04) mg/g Hb (p=0.001) in group B. Infectious complications were equally frequent in the two groups (group A: 44; group B: 37; p=0.571). Survival rate and duration of hospital stay were also comparable in the two groups. CONCLUSION: Enteral glutamine supplementation offers no advantage in patients with peritonitis or abdominal trauma.

Operative treatment of hepatic trauma in Vachira Phuket Hospital.

Descriptive study of an 8-year period, 211 patients with hepatic trauma were studied retrospectively. Most of the patients were male (81.5%). Patients mainly affected were in the third decade of life (46.9%) with an age range of 2 to 65 years old (Mean 26.1 +/- 9.8). Fifty four percent resulted from blunt and 46.4% from penetrating injuries. The most common cause of injuries was motorcycle accidents (41.2%). The injuries were graded by the hepatic injury scale (grades I to VI). There were 22 (10.4%), 62 (29.4%), 70 (33.2%), 27 (12.8%), 28 (13.3%) and 2 (0.9%) patients with grade I, II, III, IV, V and VI hepatic injuries, respectively. Forty seven percent of patients were in shock when they first arrived at the emergency room. One hundred and sixty five patients (78.2%) had 375 associated injuries. Seventy three percent of patients had low grade hepatic injuries (grades I to III), the remainder (27%) had high grade hepatic injuries (grades IV to VI). Operative treatment of hepatic injuries varied according to degree of injury. Low grade hepatic injuries amenable to relatively simple operative treatment. Nineteen deaths (12.3%) occurring in this group were attributed to the commonly encountered associated injuries inside and outside the abdomen, which were more frequently seen after blunt trauma (89.5%). High-grade hepatic injuries required major techniques. Thirty four of these patients died (59.6%), death was related to the injury itself (91.2%), which were more frequently seen after blunt trauma (85%). During operation, suture ligature of the bleeding point, or hepatorrhaphy stopped the bleeding in most circumstances. Perihepatic packing was a useful procedure when termination of the operation was considered necessary in order to prevent the development of hypothermia, acidosis and coagulopathy. Perihepatic packing was used for treatment of 73% of high grade hepatic injuries and yielded 65.5% survival rate. The results were 59 patients had complication (morbidity 28%) and 53 patients in the present study died (mortality 25.1%). Thirty one patients (14.7%) died of hepatic cause, whereas 22 patients (10.4%) died of non hepatic causes. Exsanguination and associated head injuries were the major cause of death (83%). Nonsurvivors had a significantly higher shock, blunt injury, associated injury and high grade hepatic injury than survivors (p < 0.005). The high mortality and morbidity can be achieved by well regulated motorcycle accident prevention measures and well prehospital care.

Manejo del abdomen abierto: experiencia en el Hospìtal "Jesús Yerena" de Lidice / Management of the abdomen: experience in the Hospital \"Jesus Yerena\" de Lidice

Analizar el manejo de pacientes con abdomen abierto, para establecer las pautas con respecto a las indicaciones, técnica quirúrgica utilizada y relaparotomías. Hospital General Dr. Jesús Yerena de Lidice. Servicio de Cirugía General. Estudio de tipo retrospectivo basado en la revisión de historias médicas, de 50 pacientes tratados con abdomen abierto, entre mayo de 1997 y mayo de 2002. Del total de pacientes estudiados; 42 fueron del sexo masculino y 8 del sexo femenino, la edad promedio fue de 38,9 años (Rango: 15-82 años). El 50 por ciento de estos pacientes ingresaron por presentar trauma abdominal, 30 por ciento por infección abdominal, y 20 por ciento por otras causas. Las indicaciones para el manejo abierto del abdomen fueron: Líquido purulento en cavidad (54 por ciento), aumento de la presión intraabdominal (10 por ciento), compromiso vascular de las asas (4 por ciento), empaquetamiento intraabdominal (8 por ciento), pancreatitis (16 por ciento), fístulas intestinales (8 por ciento). La bolsa de Bogotá fue el método más utilizado, para el manejo abierto del abdomen. En total se realizaron 251 intervenciones en 50 pacientes, siendo lo más frecuente de 2 a 3 laparotomías por paciente (rango 1-15 laparotomías), con un intervalo promedio entre cada laparotomía de 24-48 horas. Fallecieron un total de 18 pacientes. El manejo abierto del abdomen, está indicado en pacientes que necesitan más de 2 laparotomías, como en procesos infecciosos severos, en la cirugía de control de daños, en pacientes con presión intraabdominal elevada, pacientes con packing intraabdominal y cuando es necesaria la revisión de la viabilidad de las asas, sometidas a compromiso vascular en la intervención inicial. El abdomen debe cerrarse definitivamente cuando se evidencia resolución de la patología intraabdominal, y se comprueba que no hay contenido purulento dentro del abdomen. La morbi-mortalidad de éstos pacientes aumenta según el número de laparotomías, y el tiempo que permanece.

Mortality and morbidity of abdominal inferior vena-caval injuries

To evaluate the outcome of abdominal inferior vena-caval [IVC] injuries in patients presented to Accident and Emergency Department, Lady Reading Hospital, Peshawar. Design: An observational study. Place and Duration of Study: The study was conducted at Postgraduate Medical Institute [PGMI]/Lady Reading Hospital, Peshawar, from January 1995 to January 2003, Patients and Case records of all patients operated within specified period for vascular trauma having injuries to the abdominal inferior vena cava. In all cases vascular trauma management was done mainly on clinical assessment in a low equipped set up. Data on age, gender, mechanism, nature and location of inferior vena-caval injuries, other vascular and non-vascular injuries were recorded. There were 22 patients, 77.27% male and 22.72% female. Age ranged from 10 to 40 years with mean age of 25.09 years. Majority of injuries were caused by penetrating injury [77.27%], blunt injury in 04.54% and 18.87% were iatrogenic. Majority [95.45%] were having single laceration of inferior vena cava and 04.54% were having more than one laceration. Associated vascular injuries involved aortic 9.09%, internal iliac in 4.54% and renal vein in 4.54%. Most common associated non-vascular injury involved small intestine [72.72%] and large gut [50%]. Inferior vena-caval injuries carries high mortality rate. When associated with multiple organ injuries and retrohepatic inferior vena-caval injuries are almost fatal